Product Details Page . DH most commonly involves the facial surfaces of maxillary and mandibular permanent teeth. Panagakos F, Schiff T, Guignon A. Dentin hypersensitivity: effective treatment with an in-office desensitizing paste containing 8% arginine and calcium carbonate. Lai HY, Lee S, Toh SW, Li Y, Mateo LR, Morrion BM, Zhang Y: The clinical efficacy of a new dentifrice with zinc on plaque and gingivitis. Get the best deals for COLGATE Sensitive Pro Relief Complete Protection Toothpaste 110g. Clinically proven Instant and lasting Sensitivity relief*. Benefits. Post-hoc analysis revealed a significant reduction in DH scores in treatment arms compared to control on completing the six-week trial (p<0.05). The Colgate Sensitive Pro Relief range features toothpastes that provide relief for sensitive teeth while addressing other common oral health concerns: Colgate Sensitive Pro Relief Repair and Prevent to protect against gingival recession. COLGATE. CONCLUSION: The study results support the following conclusions: (1) Colgate Sensitive Pro-Relief toothpaste provides a significantly more reduction in dentin hypersensitivity than Sensodyne. IRB-1351/DUHS/Approval/2019/184. Though all bioactive agents have a significant treatment effect in reducing DH, there is currently no consensus on the unequivocal efficacy of any product or bioactive agent used for managing the condition due to huge variations and heterogeneity in the conduct of clinical trials on DH [6]. Pak Oral Dent J. compared Colgate Sensitive Pro Relief to another leading brand that desensitizes with a 2% potassium ion formula. HOW DOES Colgate SENSITIVE INSTANT Relief Repair & Prevent WORK? A comparative clinical study investigating the efficacy of a dentifrice containing 8% strontium acetate and 1040 ppm fluoride in a silica base and a control dentifrice containing 1450 ppm fluoride in a silica base to provide immediate relief of dentin hypersensitivity. For more great Dental Care products like toothpaste and mouthwash, continue browsing online and buy in-store at B&M. Colgate Sensitive Instant Relief Toothpaste 75ml Product code: 326795 2.49 Subject to availability - visit your nearest store The participants with self-reported sensitivity in teeth were clinically diagnosed with DH. This site is intended for healthcare professionals only. No side effects, apart from money not well spent. With regular use, it reduces teeth sensitivity and helps to strengthen gums and prevent gum recession. Based on the synthesis of study results, we can conclude that Pro-argin in Colgate Sensitive Pro-relief and 8% strontium acetate in Sensodyne Rapid Action both are effective for pain relief in one minute after application in DH with better immediate treatment response of Pro-argin than strontium acetate. Colgate Professional has resources to help your patients understand what causes enamel erosion and how to avoid falling into those traps. Grading of Recommendations, Assessment, Development and Evaluations. Lavender SA, Petrou I, Heu R, Stranick MA, Cummins D, Kilpatrick-Liverman L, et al. We discuss how this innovative technology works to provide patients with rapid and long-lasting relief from dentin hypersensitivity. 2 Docimo et al. The makers of Colgate Sensitive Pro-Relief and its rival, Sensodyne Rapid Relief, have been dobbing each other into the health regulator over advertising claims that the toothpastes give users "instant" relief to pain from sensitive teeth. HOW LONG CAN A PATIENT USE Colgate SENSITIVE INSTANT Relief Repair & Prevent? Friedman Test was used to observe post-application change in treatment responses within the group for 6weeks. 2017;30(4):2216. Kp nu. Colgate Tandpasta Sensitive Instant Relief Whitening. 1):8A-15A. Correspondence to Dentifrices-containing Pro-argin showed a significant reduction in DH with mean scores of (3.052.17) followed by strontium acetate (3.751.97) followed by FCPS (5.301.83) one minute after application. Am J Dent. 4.4 5 0 198 198 Colgate Sensitive Pro-Relief Gum Therapy toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. All participants were instructed to dry the tooth surface with the cotton ball and apply a paste of about half-inch length on the dried surface for one minute, then brush the teeth twice daily after breakfast and before sleep as per directions demonstratedon the study model. Shrimathi S. Effect of BiominF, NovaminR, Argin and nanohydroxy particles containing dentifrices on dentine hypersensitivity and gingivitis among 3544 years aged population of Madurai district: a randomized controlled trial (RCT). The impact of FCPS, Pro-argin, and strontium acetate-based treatments of DH on the oral health-related quality of life together with the difference in the effectiveness of treatments were assessed individually rather than in groups in the current six-week trial. 2016;27(4):916. We observed the varying treatment response at different efficacy intervals that could be due to the varying degree of patient's response to pain-provoking stimuli in DH. There is no problem with every day and prolonged use. Article Hu ML, Zheng G, Lin H, Yang M, Zhang YD, Han JM. Mintsmak. See patient relevant information on Colgate.com. The prime focus of treatment nowadays is based on the exploration of novel materials to remineralise the exposed tubular endings and mimic and restore the structure of the dentin [11]. Colgate Sensitive PRO-Relief provides you relief from sudden shocks of pain and long-term sensitivity with regular use. Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste provides instant* and long-lasting sensitivity relief and lasting gum protection: PRO-ARGIN Technology repairs sensitive areas of the teeth for instant and long-lasting pain relief1,2, Zinc helps to strengthen gums and to prevent recession a key cause of sensitivity3. Purchased in August 2019 at Coles for $5. In each study, a single fingertip application of Colgate Sensitive Pro Relief was found to provide significant immediate relief relative to the comparative toothpaste, a result that was maintained over the subsequent three days with twice-daily brushing with the same toothpaste. Trials. These participants were randomized equally by the principal investigator into four entitled treatment arms using computer-generated random sequence numbers, and treatments were allocated randomly using sequentially numbered, opaque, sealed, and stapled envelopes (SNOSE). A meta-analysis by Yang et al. PubMed 3rd edition, Public Health England 2014. [28] reporting the immediate effect of 8% strontium acetate in alleviating clinical symptoms of DH with clinically and statistically significant (<0.001) measures relative to baseline [26]. Favaro Zeola L, Soares PV, Cunha-Cruz J. J Clin Dent 20 (2009), special issue 17-22, 3. Pessoa, Loretto et al. Exclusive Pro-Argin formula. PubMed Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. J Clin Dent 2009; 20 (Spec Iss): 17-22. Pro-Argin technology is occlusive. The Sensitive Pro-Relief Multi-Protection toothpaste by Colgate thoroughly cleans your teeth, while providing you with relief from sensitive tooth pain. Colgate Sensitive Pro-Relief toothpaste is a revolutionary and one-of-its kind remedy that can provide consumers suffering from Sensitivity the much needed instant and long lasting relief . Desensitizing toothpastes depolarize the nerves to reduce pain signals to the brain, while occlusives block the dentin tubules to prevent painful stimuli affecting dentinal fluids. Tandkrmen remineraliserar tandemaljen fr att ge bttre motstnd mot syraattacker. 2009;22:3A-7A. Google Scholar. Pro-Argin showed a greater reduction in DH with mean scores of (1.340.68) (4.201.70) (3.052.17) followed by strontium acetate (1.570.81) (4.651.87) (3.751.97) on SCASS and VAS for mechanical and water jet stimuli, one minute after application. Statistical Package for the Social Sciences software v.21.0. Colgate Sensitive Pro-Relief Multi Protection Toothpaste provides clinically proven instant and lasting relief for sensitive teeth For instant relief, apply directly to each sensitive tooth with finger tip and gently massage for 1 minute, up to twice daily Schiff T, Delgado E, Zhang Y, Cummins D, DeVizio W, Mateo L. Clinical evaluation of the efficacy of an in-office desensitizing paste containing 8% arginine and calcium carbonate in providing instant and lasting relief of dentin hypersensitivity. 1). Colgate Sensitive Pro Relief offers a solution that is clinically proven to relieve sensitivity pain. Yang ZY, Wang F, Lu K, Li YH, Zhou Z. Arginine-containing desensitizing toothpaste for the treatment of dentin hypersensitivity: a meta-analysis. Department of Oral Biology, Dr. Ishrat-Ul-Ebad Khan Institute of Oral Health Sciences (DIKIOHS), Dow University of Health Sciences, Karachi, Pakistan, Department of Oral Biology, Dow Dental College, Dow University of Health Sciences, Karachi, Pakistan, Department of Research, School of Public Health, Dow University of Health Sciences, Karachi, Pakistan, You can also search for this author in reporting the instant relief from DH by 44.1% with Pro-argin on SCASS. J Evid Based Dent Pract. Colgate Sensitive Pro Relief can be applied directly to the affected area for almost instant relief. it is in a rubbish bin now. [33] again reported a 54% clinical reduction in DH with Pro-argin in eight weeks clinical trial using SCASS. Treatment difference between FCPS, Pro-argin, and 8% strontium acetate was not statistically significant with a p>0.05 for sustained pain relief in DH. Apotekets varuid 29483 Varunummer 207000 Kategori Tandkrm, Ilningar i tnderna Varumrke Arginine, Calcium Carbonate, Aqua, Sorbitol, Aroma, Poloxamer 407, Sodium Monofluorophosphate, Cocamidopropyl betaine, Zinc oxide, Benzyl Alcohol, Cellulose Gum, Zinc Citrate, Sodium Bicarbonate, Tetrasodium Pyrophosphate, Xantham Gum, Sodium Saccharin, Sucralose, Limonene, CL77891, 1. Gillam D, Talioti E. The Management of Dentine Hypersensitivity. The treatment difference between Pro-argin and 8% strontium acetate was not statistically significant with a p>0.05 for immediate and sustained pain relief in DH and statistically significant relative to control on all clinical parameters of the SCASS and VAS. J Clin Dent 20 (2009), special issue 123-130, 2. Not all desensitizing toothpastes perform equally well. Bakri MM, Hossain MZ, Razak FA, Saqina ZH, Misroni AA, Ab-Murat N, et al. 2019;88:103170. Therefore, in the current study, we used a dental explorer and the air blast and water jet stimuli from the triple syringe of the dental unit for testing DH to control the subjective variations in treatment response. This trial was registered in an ICMJE approved registry at https://clinicaltrials.gov/) under protocol Identifier: NCT04249336 [19] following the CONSORT guidelines [20] for parallel-group randomized trials after approval from the Institutional Review Board of Dow University of Health Sciences with reference no. Paired sample T-test was used to compute mean scores to observe change relative to baseline at each time point. Plain bi-carb soda and coconut butter do a far better job at cleaning and desensitising. This toothpaste prevents sensitivity coming back by building a protective barrier that acts like . KruskalWallis test was used to compare treatment groups. Poster #0742, March 2018 AADR. Colgate Sensitive Pro-Relief r en tandkrm som ger omedelbar och varaktig lindring mot ilningar i tnderna. J Dent. The prevalence of DH was found to vary from about 5 to 62% owing to the use of different diagnostic and measuring tools and age groups in the published literature, with the best average estimate of 34% worldwide [3]. Last updated on May 11, 2021. Colgate Sensitive Pro-Relief toothpastes have been formulated to provide instant and lasting relief from the pain associated with sensitive teeth. Lasting protection with regular use. Book This site is intended for healthcare professionals only. The findings agreed with another in vitro trial by Mahmoodi et al. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. SCASS and VAS were introduced on each visit as primary and secondary outcome measures, respectively. The second null hypothesis was that mean scores for pain due to DH among different treatment groups for sustained relief remains the same, and it was considered to be rejected at a p value0.05. Colgate Sensitive Instant Relief Multiprotection Toothpaste gives you clinically proven lasting relief from sensitivity for 8 weeks when you use it twice a day. Table 3 demonstrates the percent change in the mean scores of DH on SCASS relative to baseline within the group for each treatment arm. Product Details For instant relief, apply directly to the sensitive tooth with finger tip, and massage gently for 1 minute, once a week or less frequently. The main etiological factors are abrasion and erosion that may or may not be associated with gingival recession in DH. Colgate Sensitive Instant* Relief Enamel Repair Toothpaste gives you clinically proven lasting relief** from sensitivity for 8 weeks when you use it twice a day. This clinical trial was approved by the Institutional Review Board of Dow University of Health Sciences (Ref: IRB-1351/DUHS/Approval/2019/184) and was registered under the protocol ID NCT04249336 (https://clinicaltrials.gov/ct2/show/NCT04249336) on January 30, 2020, in accordance with the CONSORT statement of the updated guidelines for reporting randomised clinical trials. . (US). Plus it has the freshness you trust from Colgate! With its unique Pro-Argin technology, this sensitive toothpaste will give you instant* relief from sensitivity as it helps to seal and repair the sensitive areas of your teeth (with continued use twice a day). There was no statistically significant treatment difference between the two (p=0.499). 2012;12(3):2208. A randomised, controlled, triple-blinded clinical trial was conducted with 140 participants clinically diagnosed with DH and equally randomized into four groups with parallel treatment assignment of FCPS, Pro-Argin, 8% strontium acetate, and sodium fluoride-based OTC dentifrices, and tested for DH with air blast, mechanical, and water jet stimuli on SCHIFF cold air sensitivity scale (SCASS) and visual analogue scale (VAS) at interim efficacy intervals of one minute, three days, two, four, and six weeks, subsequently. J Clin Periodontol. Therefore, it was considered to be rejected at a p valueof 0.05. While your patients may have dentine hypersensitivity in common, their oral care needs will vary. J Dent Probl Solut. [18] in a meta-analysis in 2020. 75 ml. J Dent. This clinical trial was not funded by any agency in public, commercial or not-for-profit sectors. 2010;21(2):568. Colgate Sensitive Instant Relief Repair & Prevent tandkrm ger dig kliniskt bevisad lngvarig lindring mot ilningar i tta veckor nr du anvnder den tv gnger om dagen. These commercially available tooth paste are one n the same thing.Both says they work in reducing the tooth senstivity due to cold intake.These may help olny during the early stages but when there is sensation to both cold and hot drinks and pain, you need to visit a dentist. Colgate SENSITIVE INSTANT Relief tannkrem med Pro-Argin teknologi gir umiddelbar* og langvarig smertelindring av ising i tennene. 2010;11:32. J Evid Based Dent Pract. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. Gently and effectively removes stains. Table 4 demonstrates a comparison between treatment groups observing better clinical efficacy in managing DH on SCASS. Our study included an Asian population, and most of the published literature was associated with the Caucasian population. Sealed channels protect against pain caused by hot, cold and sweet stimuli. However, Pro-argin showed more clinical improvement in air blast and mechanically stimulated DH compared to 8% strontium acetate, as shown in Tables 4 and 5. The relief from sensitivity offered by Colgate Sensitive Pro Relief is proven to last. 1. Today's era of flourishing research in DH is based on incorporating bioactive ingredients in commercially available oral dentifrices that can induce deep intratubular remineralisation of dental hard tissues for permanent or long-term treatment purposes. 2020;20(3):101460. Participants were asked to pick up the envelope from the box. The study's primary objective was to investigate pain relief in one minute with Pro-argin and strontium acetate in DH measured on SCASS as a primary outcome measure and VAS as a secondary outcome measure. Another study by Vu Pham and Anh Nguyen reported clinical improvement in DH by 38.9% on SCASS and 40.2% on VAS for mechanical stimulated DH immediately after application of Pro-argin [25]. Dentifrices-containing Pro-argin showed a significant reduction in DH with mean scores of (4.201.70) followed by strontium acetate (4.651.87) followed by FCPS (5.101.88) one minute after application. The dropouts of the participants at each efficacy interval may be considered the weakness of this trial that was due to COVID-19 lockdown. When it begins to interfere with oral hygiene, it can also lead to poor oral health outcomes. Colgate Toothpaste relieves the discomfort of tooth irritation by still addressing the root causes. A randomised controlled, triple-blinded, phase-3 clinical trial was conducted at the Department of Periodontology at Dr Ishrat-ul-Ebad Khan Institute of Oral Health Sciences (DIKIOHS) in Dow University of Health Sciences (DUHS), Karachi, Pakistan from September 2019 to December 2020. Docimo R, Montesani L, Maturo P, Costacurta M, Bartolino M, DeVizio W, Zhang YP, Cummins D, Dibart S, Mateo LR: Comparing the Efficacy in Reducing Dentine Hypersensitivity of a New Toothpaste Containing 8.0% Arginine, Calcium Carbonate, and 1450 ppm Fluoride to a Commercial Sensitive Toothpaste Containing 2% Potassium Ion: An Eight-Week Clinical Study in Rome, Italy. Significantly greater sensitivity reduction with twice - daily brushing compared to control toothpaste with potassium ions. Benefits: Colgate Sensitive Prevent and Repair is clinically proven to provide superior relief vs Sensodyne Extra Whitening at 8 weeks1 Long-lasting relief from hypersensitivity with continued use Superior sensitivity relief at 8 weeks vs the leading Sensodyne toothpaste variant 1 Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. For instant relief, apply directly to the sensitive tooth with finger tip, and massage gently for 1 minute, once a week or less frequently. Formulated with Pro-Argin technology, Colgate Sensitive Pro-Relief is clinically proven instant and lasting sensitivity relief*. 2. Hence, the current study outcomes, along with previously published findings, corroborate the in vitro findings of obliteration of dentinal tubules with strontium acetate impeding painful fluid movement in dentine [29]. Colgate Sensitive Plus Toothpaste developed for sensitive teeth provides sensitivity protection And helps in Enamel Repair, Cavity . Dentinal tubules occluded by bioactive glass-containing toothpaste exhibit high resistance toward acidic soft drink challenge. 5 Hines D et al. 1 Nathoo et al. In addition, participants were asked to record the overall sensitivity of their day-to-day experience on provided VAS sheets reporting pain on brushing, taking hot or cold beverages, and rinsing with tap water for the six weeks of the study. All the treatment groups subjected to testing in the present study revealed a considerable clinically significant symptomatic reduction in DH relative to the pre-treatment condition that was also statistically significant. Hines D, Rinaudi L, Xu S, Lavender S, Pilch S: The Use of Confocal Laser Scanning Microscopy and a Novel Imaging Program for Quantifying Dentine Tubule Occlusion. Tandkrmen innehller zink fr att strka tandkttet och frhindra att tandkttet drar sig tillbaka, vilket r en av de vanligaste orsakerna till att . Hines D: Poster #0742 March 2018 AADR. 2013;41(2):18794. Colgate Sensitive Pro-Relief It works by plugging the channels to block tooth sensitivity and with regular use. These fluorapatite crystals were less susceptible to acidic dissolution than hydroxyapatite crystals and thus were more desirable [13]. J Clin Periodontol. Madurai: Best Dental Science College; 2020. The comparative evaluation was done for the clinical efficacy of Pro-argin and 8% strontium acetate, and a statistically significant (p>0.05) difference was not found between these two formulations in the current study. Most sensitive toothpastes primarily numb the discomfort, whereas Colgate Sensitive Pro-Relief works to relieve sensitivity by plugging the channels that lead to sensitive tooth nerves. However, there was no significant treatment difference between dentifrices containing Pro-argin and strontium acetate (p>0.05) at each efficacy interval. Arshad, S., Zaidi, S.J.A. Ingredients *Calcium carbonate *Water Gentle whitening formula. Klubpris: 25,46 kr. Provided by the Springer Nature SharedIt content-sharing initiative. Nachar Sinus Rinse System, 4pcs Professional Baby Nasal Irrigator Portable Infant Nose Cleaner Quick Rinse Device All Natural Relief - BPA Free More Convenient. It is clinically proven for instant and lasting Sensitivity relief* How does it work? Learn more about caries in children from the resources provided on this page. J Dent. p values of<0.05 were considered as statistically significant. For instant relief, apply directly to each sensitive tooth surface and massage for one minute, up to twice a day. The authors declare that they have no competing interests (financial and non-financial) related to the article. 3. Identifier NCT 04249336. FCPS showed the highest reduction in DH on SCASS and VAS for waterjet stimuli with mean scores of (0.970.68) (1.801.73) and Pro-Argin on VAS for mechanical stimuli with mean scores of (2.151.92) in six weeks. Soft tissues were isolated with cotton rolls, and adjacent teeth were isolated with cotton pellets. California Privacy Statement, The study's primary objective was to investigate pain relief in one minute after topical application of Pro-argin and strontium acetate on sensitive teeth in DH. A study evaluating the efficacy of strontium acetate relative to arginine-based dentifrices was conducted by West et al. 2020;12(2):87. Contemp Clin Dent. Google Scholar. J Dent Res. Colgate Sensitive Pro-Relief Instant Relief works as a shield that blocks pathways to pain instantly. 2018;75:1221. Click & Collect.